Endran Healer EYE, Targeted PN Care for the Eye Area

Features of EYE Endran

• While various PN skin booster products are available, Eye Endran is a salmon-derived polynucleotide (PN) ingredient with a PN content level similar to certain specific products. It can be a reasonable choice, especially when considering continuous management. Since there may be compositional differences from PN extracted from fish other than salmon, it is important to confirm that it is a salmon-derived ingredient.
• The treatment is performed by carefully adjusting the depth of the skin layer to suit the required areas, such as under the eyes, eyelids, and around the eyes.
• 2cc of PN ingredient is injected precisely as is, without dilution with saline solution.
• Its relatively low viscosity can reduce pain during the procedure, and any localized swelling (embossing) tends to absorb relatively quickly.
• Designed specifically for the delicate eye area, it is easy to apply stably even to sensitive regions.
• In addition to eye area treatments, its low pain makes it suitable for application across the entire face, helping to improve overall skin dullness, inner dryness, and fine wrinkles.
• With skilled technique, the medication is precisely injected into the dermal layer, and after the procedure, any localized swelling around the eyes is confirmed with the patient.

What is EYE Endran (PN) Skin Booster?

Eye Endran is a skin booster that utilizes Polynucleotide (PN) ingredients specifically formulated for the skin around the eyes.

It is a precise treatment designed to improve fine wrinkles, dark circles, and inner dryness around the eyes.

This product contains PN ingredients and content similar to certain PN healers, but it is specifically designed for the thin, sensitive skin around the eyes. As a result, the injection feels smoother, reducing pain, and any localized swelling tends to subside relatively quickly.

Why EYE Endran is Needed for Eye Area Care

The skin around the eyes is much thinner and more sensitive than other parts of the face.

Due to these characteristics, it is vulnerable to external stimuli, and changes due to aging or dryness appear quickly.

The skin barrier is particularly prone to weakening, often leading to inner dryness, fine wrinkles, and bluish dark circles appearing together.

The eye area has a thin subcutaneous fat layer and a thin dermal layer, so general moisturizers or eye creams alone may have limitations in improving these issues.

Therefore, injecting PN ingredients directly into the dermal layer to induce skin regeneration can help resolve eye area concerns.

What is PN (Polynucleotide)?

PN is a high-purity, bio-derived substance extracted from salmon DNA.

Compared to PDRN, it has a larger molecular weight and is known as an ingredient with good response-inducing ability in the dermal layer.

While PDRN primarily aids in basic hydration and regeneration processes, PN can play a greater role in directly acting on the dermal layer to induce structural improvement of the skin.

PN promotes skin improvement through the following actions:

It activates fibroblasts to promote the production of collagen and elastin. This can contribute to enhanced skin elasticity, reduced fine wrinkles, and a more supple skin surface.

It increases the secretion of various growth factors such as TGF, FGF, and VEGF, aiding in skin recovery processes and promoting the regeneration of damaged tissues. Furthermore, it can help alleviate inflammatory responses, maintaining the skin in a healthy state.

It induces the regeneration of epidermal cells and strengthens the skin barrier function. By reinforcing the connections between keratinocytes, it helps prevent moisture loss and improves inner dryness.

Our skin has a barrier structure composed of bricks (keratinocytes) and cement (intercellular lipids).

PN aids in the recovery of intercellular lipids, which act like this cement, helping to inhibit moisture evaporation and simultaneously improve inner dryness and skin sensitivity.

It contributes to the restoration and increased thickness of damaged dermal tissue. This can positively impact the alleviation of dark circles caused by a thinned dermis and the improvement of fine wrinkles.

The skin forms a barrier structure composed of 'bricks' (keratinocytes) and 'cement' (intercellular lipids). PN can reinforce the role of this 'cement' to effectively prevent moisture evaporation and is expected to simultaneously improve inner dryness and sensitive skin conditions.

Understanding Embossing and Dermal Layer Injection

The dermal layer has a densely packed structure,

so when the medication is injected, the skin may temporarily swell.

This phenomenon is called 'embossing' and serves as an indicator that the medication has been properly delivered to the target dermal layer.

After the procedure, we check for any embossing with the patient and explain whether the injection was accurate.

Embossing from typical PN procedures can usually last for 3 to 7 days or more. However, Eye Endran has a thinner viscosity, meaning it tends to absorb quickly, often before a week passes. It is also known to cause relatively less pain, making it a more comfortable option for sensitive areas like the eyes.

Recommended for those who:

• Are concerned about the appearance of fine wrinkles around their eyes.
• Are also recommended for those whose eyes appear dark due to bluish dark circles. Bluish discoloration around the eyes is often caused by thin dermal layers, allowing blood vessels beneath the skin to show through. Eye Endran can subtly increase dermal thickness, helping to alleviate dark circles.
• Have rough skin texture and makeup that tends to cake due to inner dryness.
• This procedure is designed for individuals with sensitive or thin skin who feel cautious about typical lifting treatments.
• For those who use eye cream for eye area care but feel that the expected changes are not sufficient.
• Suitable for those who are concerned about fine wrinkles on their eyelids but have been told that a delicate procedure is necessary.
• Individuals who are concerned about their impression due to fine wrinkles around their eyes may consider this.

Treatment Cycle and Maintenance Period

• We generally recommend receiving a total of 3 treatments at one-month intervals.
• Thereafter, receiving additional management approximately every 6 months can help maintain the treatment effects.
• The general maintenance period is expected to be between 6 months and 1 year, and may vary depending on individual skin condition.
• We strive to minimize pain during the procedure, and any occasional swelling (embossing) usually subsides naturally within 1 to 3 days.

A Message from the Head Director

We believe that eye area treatments go beyond simply removing wrinkles; it's crucial to boost the skin's inherent healthy regenerative and recovery functions.

When consistent skincare, such as eye cream, is not enough to achieve satisfaction, a professional procedural approach can help improve the skin.

There may come a point when deep concerns around the eyes cannot be resolved with everyday topical skincare alone.

In such cases, a treatment that improves the skin's internal environment may be necessary. Particularly, methods that increase the density of the dermal layer can be beneficial.

As one such approach, you may consider the Eye Endran procedure.

We believe that if sincerity is put into treating the skin, the touch of the medical staff performing the procedure must also be delicate and sincere.

It is important to deeply consider all aspects, from precise treatment of the target area and meticulous verification processes to patient satisfaction.

Our medical team will continuously strive to meet our patients' expectations throughout all these processes.